Antidepressant-like Effects Induced by Chronic Blockade of the Purinergic 2X7 Receptor through Inhibition of Non-like Receptor Protein 1 Inflammasome in Chronic Unpredictable Mild Stress Model of Depression in Rats

OBJECTIVE: Purinergic 2X7 receptor (P2X7R) activation is known to be involved in pathogenesis of depression. Our aims were to investigate P2X7R-activated inflammasome pathways in parallel with induction of depression and to test the antidepressant-like effects of the selective P2X7R antagonist Brill...

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Publicat a:Clin Psychopharmacol Neurosci
Autors principals: Aricioglu, Feyza, Ozkartal, Ceren Sahin, Bastaskin, Tugce, Tüzün, Erdem, Kandemir, Cansu, Sirvanci, Serap, Kucukali, Cem Ismail, Utkan, Tijen
Format: Artigo
Idioma:Inglês
Publicat: Korean College of Neuropsychopharmacology 2019
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478084/
https://ncbi.nlm.nih.gov/pubmed/30905126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.9758/cpn.2019.17.2.261
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