Role of hippocampal p11 in the sustained antidepressant effect of ketamine in the chronic unpredictable mild stress model

Although ketamine shows a rapid and sustained antidepressant effect, the precise mechanisms underlying its effect are unknown. Recent studies indicate a key role of p11 (also known as S100A10) in depression-like behavior in rodents. The present study aimed to investigate the role of p11 in the antid...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: Sun, H-L, Zhou, Z-Q, Zhang, G-F, Yang, C, Wang, X-M, Shen, J-C, Hashimoto, K, Yang, J-J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872431/
https://ncbi.nlm.nih.gov/pubmed/26905413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2016.21
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