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Inhibitors of Hydrolases with an Acyl–Enzyme Intermediate

Peptidases and esterases are hydrolytic enzymes; 2–3% of all gene products are assigned to this group alone. They are therefore, an important group of target proteins for the design of new medicines and have a special importance for structure-based drug design. This is reflected in the fact that abo...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Drug Design
Glavni avtor: Klebe, Gerhard
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7176293/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-642-17907-5_23
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