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PRKAG2 Gene Expression Is Elevated and its Protein Levels Are Associated with Increased Amyloid-β Accumulation in the Alzheimer’s Disease Brain

Increased amyloid-β (Aβ) accumulation associated with abnormal autophagy-lysosomal activity and nutrient kinase dysregulation are common features in Alzheimer’s disease (AD) brain. Recent studies have identified PRKAG2 and TIPRL genes that control nutrient kinase regulated autophagy, and here we det...

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Bibliografiske detaljer
Udgivet i:J Alzheimers Dis
Main Authors: Bharadwaj, Prashant, Martins, Ralph N.
Format: Artigo
Sprog:Inglês
Udgivet: IOS Press 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7175932/
https://ncbi.nlm.nih.gov/pubmed/32039845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-190948
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