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CRISPR Based Synthetic Transcription Factors In Vivo: The Future of Therapeutic Cellular Programming
Pinpoint control over endogenous gene expression in vivo has long been a fevered dream for clinicians and researchers alike. With the recent repurposing of programmable, RNA-guided DNA endonucleases from the CRISPR bacterial immune system, this dream is becoming a powerful reality. Engineered CRISPR...
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| Publicado no: | Cell Syst |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7175797/ https://ncbi.nlm.nih.gov/pubmed/31972154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2019.10.003 |
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