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CRISPR Based Synthetic Transcription Factors In Vivo: The Future of Therapeutic Cellular Programming

Pinpoint control over endogenous gene expression in vivo has long been a fevered dream for clinicians and researchers alike. With the recent repurposing of programmable, RNA-guided DNA endonucleases from the CRISPR bacterial immune system, this dream is becoming a powerful reality. Engineered CRISPR...

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Dettagli Bibliografici
Pubblicato in:Cell Syst
Autori principali: Pandelakis, Matthew, Delgado, Elizabeth, Ebrahimkhani, Mo R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7175797/
https://ncbi.nlm.nih.gov/pubmed/31972154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2019.10.003
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