Gerontoxanthone I and Macluraxanthone Induce Mitophagy and Attenuate Ischemia/Reperfusion Injury

Mitophagy is a crucial process in controlling mitochondrial biogenesis. Balancing mitophagy and mitochondrial functions is required for maintaining cellular homeostasis. In this study, we found that Gerontoxanthone I (GeX1) and Macluraxanthone (McX), xanthone derivatives isolated from Garcinia bract...

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Publicado en:Front Pharmacol
Autores principales: Xiang, Qian, Wu, Man, Zhang, Li, Fu, Wenwei, Yang, Jinling, Zhang, Baojun, Zheng, Zhaoqing, Zhang, Hong, Lao, Yuanzhi, Xu, Hongxi
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7175665/
https://ncbi.nlm.nih.gov/pubmed/32351391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00452
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