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Kindlin Assists Talin to Promote Integrin Activation

Integrin αIIbβ3 is a predominant type of integrin abundantly expressed on the surface of platelets and its activation regulates the process of thrombosis. Talin and kindlin are cytoplasmic proteins that bind to integrin and modulate its affinity for extracellular ligands. Although the molecular deta...

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Foilsithe in:Biophys J
Main Authors: Haydari, Zainab, Shams, Hengameh, Jahed, Zeinab, Mofrad, Mohammad R.K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Biophysical Society 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7175420/
https://ncbi.nlm.nih.gov/pubmed/32191864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.02.023
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