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Kindlin Assists Talin to Promote Integrin Activation

Integrin αIIbβ3 is a predominant type of integrin abundantly expressed on the surface of platelets and its activation regulates the process of thrombosis. Talin and kindlin are cytoplasmic proteins that bind to integrin and modulate its affinity for extracellular ligands. Although the molecular deta...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Haydari, Zainab, Shams, Hengameh, Jahed, Zeinab, Mofrad, Mohammad R.K.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7175420/
https://ncbi.nlm.nih.gov/pubmed/32191864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.02.023
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