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Kindlin Is Mechanosensitive: Force-Induced Conformational Switch Mediates Cross-Talk among Integrins

Mechanical stresses directly regulate the function of several proteins of the integrin-mediated focal adhesion complex as they experience intra- and extracellular forces. Kindlin is a largely overlooked member of the focal adhesion complex whose roles in cellular mechanotransduction are only recentl...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Jahed, Zeinab, Haydari, Zainab, Rathish, Akshay, Mofrad, Mohammad R.K.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428901/
https://ncbi.nlm.nih.gov/pubmed/30819565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.01.038
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