TP53 Mutations in Serum Circulating Cell-Free Tumor DNA As Longitudinal Biomarker for High-Grade Serous Ovarian Cancer

The aim of this study was to determine an optimal workflow to detect TP53 mutations in baseline and longitudinal serum cell free DNA (cfDNA) from high-grade serous ovarian carcinomas (HGSOC) patients and to define whether TP53 mutations are suitable as biomarker for disease. TP53 was investigated in...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Vitale, Silvia R., Groenendijk, Floris H., van Marion, Ronald, Beaufort, Corine M., Helmijr, Jean C., Jan Dubbink, Hendrikus, N. M. Dinjens, Winand, Ewing-Graham, Patricia C., Smolders, Ramon, van Doorn, Helena C., Boere, Ingrid A., Berns, Els M. J. J., Helleman, Jozien, Jansen, Maurice P. H. M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7175353/
https://ncbi.nlm.nih.gov/pubmed/32156073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10030415
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