In Vivo Assembly of Nanoparticles Achieved through Synergy of Structure‐Based Protein Engineering and Synthetic DNA Generates Enhanced Adaptive Immunity

Nanotechnologies are considered to be of growing importance to the vaccine field. Through decoration of immunogens on multivalent nanoparticles, designed nanovaccines can elicit improved humoral immunity. However, significant practical and monetary challenges in large‐scale production of nanovaccine...

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Publicat a:Adv Sci (Weinh)
Autors principals: Xu, Ziyang, Wise, Megan C., Chokkalingam, Neethu, Walker, Susanne, Tello‐Ruiz, Edgar, Elliott, Sarah T. C., Perales‐Puchalt, Alfredo, Xiao, Peng, Zhu, Xizhou, Pumroy, Ruth A., Fisher, Paul D., Schultheis, Katherine, Schade, Eric, Menis, Sergey, Guzman, Stacy, Andersen, Hanne, Broderick, Kate E., Humeau, Laurent M., Muthumani, Kar, Moiseenkova‐Bell, Vera, Schief, William R., Weiner, David B., Kulp, Daniel W.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Full Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7175333/
https://ncbi.nlm.nih.gov/pubmed/32328416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.201902802
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