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Testing the Pharmacokinetic Interactions of 24 Colonic Flavonoid Metabolites with Human Serum Albumin and Cytochrome P450 Enzymes

Flavonoids are abundant polyphenols in nature. They are extensively biotransformed in enterocytes and hepatocytes, where conjugated (methyl, sulfate, and glucuronide) metabolites are formed. However, bacterial microflora in the human intestines also metabolize flavonoids, resulting in the production...

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Bibliografske podrobnosti
izdano v:Biomolecules
Main Authors: Mohos, Violetta, Fliszár-Nyúl, Eszter, Lemli, Beáta, Zsidó, Balázs Zoltán, Hetényi, Csaba, Mladěnka, Přemysl, Horký, Pavel, Pour, Milan, Poór, Miklós
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7175153/
https://ncbi.nlm.nih.gov/pubmed/32155912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10030409
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