Interactions of resveratrol and its metabolites (resveratrol-3-sulfate, resveratrol-3-glucuronide, and dihydroresveratrol) with serum albumin, cytochrome P450 enzymes, and OATP transporters

Resveratrol (RES) is a widely-known natural polyphenol which is also contained by several dietary supplements. Large doses of RES can result in high micromolar levels of its sulfate and glucuronide conjugates in the circulation, due to the high presystemic metabolism of the parent polyphenol. Pharma...

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Auteurs principaux: Miklós Poór, Hana Kaci, Slávka Bodnárová, Violetta Mohos, Eszter Fliszár-Nyúl, Sándor Kunsági-Máté, Csilla Özvegy-Laczka, Beáta Lemli
Format: Artigo
Langue:Inglês
Publié: Elsevier 2022-07-01
Collection:Biomedicine & Pharmacotherapy
Sujets:
Resveratrol metabolites
Resveratrol-3-sulfate
Resveratrol-3-glucuronide
Dihydroresveratrol
Human serum albumin
Cytochrome P450
Accès en ligne:http://www.sciencedirect.com/science/article/pii/S075333222200525X
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