Effect of Intravenous Zoledronic Acid on Tibiofemoral Cartilage Volume Among Patients With Knee Osteoarthritis With Bone Marrow Lesions: A Randomized Clinical Trial

IMPORTANCE: A proof-of-principle study suggested that intravenous zoledronic acid may reduce knee pain and the size of bone marrow lesions in people with knee osteoarthritis, but data from large trials are lacking. OBJECTIVE: To determine the effects of intravenous zoledronic acid on knee cartilage...

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Bibliografiske detaljer
Udgivet i:JAMA
Main Authors: Cai, Guoqi, Aitken, Dawn, Laslett, Laura L., Pelletier, Jean-Pierre, Martel-Pelletier, Johanne, Hill, Catherine, March, Lyn, Wluka, Anita E., Wang, Yuanyuan, Antony, Benny, Blizzard, Leigh, Winzenberg, Tania, Cicuttini, Flavia, Jones, Graeme
Format: Artigo
Sprog:Inglês
Udgivet: American Medical Association 2020
Fag:
Original Investigation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7175085/
https://ncbi.nlm.nih.gov/pubmed/32315057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2020.2938
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