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Simulation of the Effects of Extracellular Calcium Changes Leads to a Novel Computational Model of Human Ventricular Action Potential With a Revised Calcium Handling

The importance of electrolyte concentrations for cardiac function is well established. Electrolyte variations can lead to arrhythmias onset, due to their important role in the action potential (AP) genesis and in maintaining cell homeostasis. However, most of the human AP computer models available i...

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Pubblicato in:Front Physiol
Autori principali: Bartolucci, Chiara, Passini, Elisa, Hyttinen, Jari, Paci, Michelangelo, Severi, Stefano
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7174690/
https://ncbi.nlm.nih.gov/pubmed/32351400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00314
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