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Role of Kupffer cells in liver injury induced by CpG oligodeoxynucleotide and flucloxacillin in mice

CpG oligodeoxynucleotide (CpG-ODN) is a Toll-like receptor 9 (TLR9) agonist that can induce innate immune responses. In a previous study, flucloxacillin (FLUX; 100 mg/kg, gavage)-induced liver injury in mice was enhanced by co-administration of CpG-ODN (40 μg/mouse, intraperitoneally). In this study...

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Bibliographische Detailangaben
Veröffentlicht in:EXCLI J
Hauptverfasser: Gao, Yuying, Song, Binbin, Aoki, Shigeki, Ito, Kousei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Leibniz Research Centre for Working Environment and Human Factors 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7174572/
https://ncbi.nlm.nih.gov/pubmed/32327959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2020-1103
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