Smooth-muscle-derived WNT5A augments allergen-induced airway remodelling and Th2 type inflammation

Asthma is a heterogeneous disease characterized by chronic inflammation and structural changes in the airways. The airway smooth muscle (ASM) is responsible for airway narrowing and an important source of inflammatory mediators. We and others have previously shown that WNT5A mRNA and protein express...

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Publicado no:Sci Rep
Main Authors: Koopmans, Tim, Hesse, Laura, Nawijn, Martijn C., Kumawat, Kuldeep, Menzen, Mark H., Sophie T. Bos, I., Smits, Ron, Bakker, Elvira R. M., van den Berge, Maarten, Koppelman, Gerard H., Guryev, Victor, Gosens, Reinoud
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7174298/
https://ncbi.nlm.nih.gov/pubmed/32317758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-63741-x
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