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TGF-β-Activated Kinase 1 (TAK1) Signaling Regulates TGF-β-Induced WNT-5A Expression in Airway Smooth Muscle Cells via Sp1 and β-Catenin

WNT-5A, a key player in embryonic development and post-natal homeostasis, has been associated with a myriad of pathological conditions including malignant, fibroproliferative and inflammatory disorders. Previously, we have identified WNT-5A as a transcriptional target of TGF-β in airway smooth muscl...

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Detalhes bibliográficos
Main Authors: Kumawat, Kuldeep, Menzen, Mark H., Slegtenhorst, Ralph M., Halayko, Andrew J., Schmidt, Martina, Gosens, Reinoud
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984265/
https://ncbi.nlm.nih.gov/pubmed/24728340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094801
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