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Cigarette smoke exposure decreases CFLAR expression in the bronchial epithelium, augmenting susceptibility for lung epithelial cell death and DAMP release

Cigarette smoking is a major risk factor for the inflammatory disease, chronic obstructive pulmonary disease (COPD). The mechanism by which cigarette smoke (CS) induces chronic lung inflammation is still largely unknown. We hypothesize that immunogenic airway epithelial cell death is involved in the...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Faiz, Alen, Heijink, Irene H., Vermeulen, Cornelis J., Guryev, Victor, van den Berge, Maarten, Nawijn, Martijn C., Pouwels, Simon D.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6102306/
https://ncbi.nlm.nih.gov/pubmed/30127367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30602-7
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