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Cigarette smoke exposure decreases CFLAR expression in the bronchial epithelium, augmenting susceptibility for lung epithelial cell death and DAMP release

Cigarette smoking is a major risk factor for the inflammatory disease, chronic obstructive pulmonary disease (COPD). The mechanism by which cigarette smoke (CS) induces chronic lung inflammation is still largely unknown. We hypothesize that immunogenic airway epithelial cell death is involved in the...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Faiz, Alen, Heijink, Irene H., Vermeulen, Cornelis J., Guryev, Victor, van den Berge, Maarten, Nawijn, Martijn C., Pouwels, Simon D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6102306/
https://ncbi.nlm.nih.gov/pubmed/30127367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30602-7
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