Targeted Melanoma Radiotherapy Using Ultrasmall (177)Lu-Labeled α-Melanocyte Stimulating Hormone-Functionalized Core-Shell Silica Nanoparticles

Lutetium-177 ((177)Lu) radiolabeled ultrasmall (~6 nm dia.) fluorescent core-shell silica nanoparticles (Cornell prime dots or C’ dots) were developed for improving efficacy of targeted radiotherapy in melanoma models. PEGylated C’ dots were surface engineered to display 10–15 alpha melanocyte stimu...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Zhang, Xiuli, Chen, Feng, Turker, Melik Z., Ma, Kai, Zanzonico, Pat, Gallazzi, Fabio, Shah, Manankumar A., Prater, Austin R., Wiesner, Ulrich, Bradbury, Michelle S., McDevitt, Michael R., Quinn, Thomas P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7171978/
https://ncbi.nlm.nih.gov/pubmed/32120314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2020.119858
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