Targeted Melanoma Radiotherapy Using Ultrasmall (177)Lu-Labeled α-Melanocyte Stimulating Hormone-Functionalized Core-Shell Silica Nanoparticles

Lutetium-177 ((177)Lu) radiolabeled ultrasmall (~6 nm dia.) fluorescent core-shell silica nanoparticles (Cornell prime dots or C’ dots) were developed for improving efficacy of targeted radiotherapy in melanoma models. PEGylated C’ dots were surface engineered to display 10–15 alpha melanocyte stimu...

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Publicado en:Biomaterials
Main Authors: Zhang, Xiuli, Chen, Feng, Turker, Melik Z., Ma, Kai, Zanzonico, Pat, Gallazzi, Fabio, Shah, Manankumar A., Prater, Austin R., Wiesner, Ulrich, Bradbury, Michelle S., McDevitt, Michael R., Quinn, Thomas P.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7171978/
https://ncbi.nlm.nih.gov/pubmed/32120314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2020.119858
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