Ultrasmall Core-Shell Silica Nanoparticles for Precision Drug Delivery in a High-Grade Malignant Brain Tumor Model

PURPOSE: Small molecule inhibitors have revolutionized treatment of certain genomically-defined solid cancers. Despite breakthroughs in treating systemic disease, central nervous system (CNS) metastatic progression is common, and advancements in treating CNS malignancies remain sparse. By improving...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Juthani, Rupa, Madajewski, Brian, Yoo, Barney, Zhang, Li, Chen, Pei-Ming, Chen, Feng, Turker, Melik Z., Ma, Kai, Overholtzer, Michael, Longo, Valerie A., Carlin, Sean, Aragon-Sanabria, Virginia, Huse, Jason, Gonen, Mithat, Zanzonico, Pat, Rudin, Charles M., Wiesner, Ulrich, Bradbury, Michelle S., Brennan, Cameron W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942644/
https://ncbi.nlm.nih.gov/pubmed/31515460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-1834
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