Increase in Endogenous Glucose Production With SGLT2 Inhibition Is Unchanged by Renal Denervation and Correlates Strongly With the Increase in Urinary Glucose Excretion

OBJECTIVE: Sodium–glucose cotransporter 2 (SGLT2) inhibition causes an increase in endogenous glucose production (EGP). However, the mechanisms are unclear. We studied the effect of SGLT2 inhibitors on EGP in subjects with type 2 diabetes (T2D) and without diabetes (non-DM) in kidney transplant reci...

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Dettagli Bibliografici
Pubblicato in:Diabetes Care
Autori principali: Solis-Herrera, Carolina, Daniele, Giuseppe, Alatrach, Mariam, Agyin, Christina, Triplitt, Curtis, Adams, John, Patel, Rupal, Gastaldelli, Amalia, Honka, Henri, Chen, Xi, Abdul-Ghani, Muhammad, Cersosimo, Eugenio, Del Prato, Stephano, DeFronzo, Ralph
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2020
Soggetti:
Emerging Therapies: Drugs and Regimens
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7171949/
https://ncbi.nlm.nih.gov/pubmed/32144165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc19-2177
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