Evidence Against an Important Role of Plasma Insulin and Glucagon Concentrations in the Increase in EGP Caused by SGLT2 Inhibitors

Sodium–glucose cotransport 2 inhibitors (SGLT2i) lower plasma glucose but stimulate endogenous glucose production (EGP). The current study examined the effect of dapagliflozin on EGP while clamping plasma glucose, insulin, and glucagon concentrations at their fasting level. Thirty-eight patients wit...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Alatrach, Mariam, Laichuthai, Nitchakarn, Martinez, Robert, Agyin, Christina, Ali, Ali Muhammed, Al-Jobori, Hussein, Lavynenko, Olga, Adams, John, Triplitt, Curtis, DeFronzo, Ralph, Cersosimo, Eugenio, Abdul-Ghani, Muhammad
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2020
Assuntos:
Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7085246/
https://ncbi.nlm.nih.gov/pubmed/31915153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db19-0770
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