Evidence Against an Important Role of Plasma Insulin and Glucagon Concentrations in the Increase in EGP Caused by SGLT2 Inhibitors

Sodium–glucose cotransport 2 inhibitors (SGLT2i) lower plasma glucose but stimulate endogenous glucose production (EGP). The current study examined the effect of dapagliflozin on EGP while clamping plasma glucose, insulin, and glucagon concentrations at their fasting level. Thirty-eight patients wit...

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Dades bibliogràfiques
Publicat a:Diabetes
Autors principals: Alatrach, Mariam, Laichuthai, Nitchakarn, Martinez, Robert, Agyin, Christina, Ali, Ali Muhammed, Al-Jobori, Hussein, Lavynenko, Olga, Adams, John, Triplitt, Curtis, DeFronzo, Ralph, Cersosimo, Eugenio, Abdul-Ghani, Muhammad
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2020
Matèries:
Pathophysiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7085246/
https://ncbi.nlm.nih.gov/pubmed/31915153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db19-0770
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