Lattice complex assembled by noncompetitive anti-EGFR antibodies regulates actin cytoskeletal reorganization

BACKGROUND: Recent evidence of clinical trials highlights that the combination of two noncompetitive anti-EGFR antibodies can benefit patients with several cancers. Previous studies propose that a lattice complex assembled by antibodies and EGFR down-regulates surface EGFR by rapid internalization o...

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Cell Int
Hauptverfasser: Huang, Dianshuai, Lu, Tianqi, Du, Xingyu, Xi, Xi, Zhang, Xin, Zhang, Xitian, Zhang, Haoran, Sun, Fei
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Primary Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7171787/
https://ncbi.nlm.nih.gov/pubmed/32336949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01204-z
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