α-Synuclein-specific T cell reactivity is associated with preclinical and early Parkinson’s disease

A diagnosis of motor Parkinson’s disease (PD) is preceded by a prolonged premotor phase with accumulating neuronal damage. Here we examined the temporal relation between α-synuclein (α-syn) T cell reactivity and PD. A longitudinal case study revealed that elevated α-syn-specific T cell responses wer...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Lindestam Arlehamn, Cecilia S., Dhanwani, Rekha, Pham, John, Kuan, Rebecca, Frazier, April, Rezende Dutra, Juliana, Phillips, Elizabeth, Mallal, Simon, Roederer, Mario, Marder, Karen S., Amara, Amy W., Standaert, David G., Goldman, Jennifer G., Litvan, Irene, Peters, Bjoern, Sulzer, David, Sette, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7171193/
https://ncbi.nlm.nih.gov/pubmed/32313102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15626-w
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