Widespread tau-specific CD4 T cell reactivity in the general population

Tau protein is found to be aggregated and hyper-phosphorylated (p-tau) in many neurological disorders, including Parkinson’s disease (PD) and related parkinsonisms, Alzheimer’s disease, traumatic brain injury and even in normal aging. While not known to produce autoimmune responses, we hypothesized...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Arlehamn, Cecilia S. Lindestam, Pham, John, Alcalay, Roy N., Frazier, April, Shorr, Evan, Carpenter, Chelsea, Sidney, John, Dhanwani, Rekha, Agin-Liebes, Julian, Garretti, Francesca, Amara, Amy W., Standaert, David G., Phillips, Elizabeth J., Mallal, Simon A., Peters, Bjoern, Sulzer, David, Sette, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581570/
https://ncbi.nlm.nih.gov/pubmed/31085590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1801506
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