α-Synuclein-specific T cell reactivity is associated with preclinical and early Parkinson’s disease

A diagnosis of motor Parkinson’s disease (PD) is preceded by a prolonged premotor phase with accumulating neuronal damage. Here we examined the temporal relation between α-synuclein (α-syn) T cell reactivity and PD. A longitudinal case study revealed that elevated α-syn-specific T cell responses wer...

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Publicado en:Nat Commun
Autores principales: Lindestam Arlehamn, Cecilia S., Dhanwani, Rekha, Pham, John, Kuan, Rebecca, Frazier, April, Rezende Dutra, Juliana, Phillips, Elizabeth, Mallal, Simon, Roederer, Mario, Marder, Karen S., Amara, Amy W., Standaert, David G., Goldman, Jennifer G., Litvan, Irene, Peters, Bjoern, Sulzer, David, Sette, Alessandro
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7171193/
https://ncbi.nlm.nih.gov/pubmed/32313102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15626-w
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