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Increased pathogenicity of pneumococcal serotype 1 is driven by rapid autolysis and release of pneumolysin
Streptococcus pneumoniae serotype 1 is the predominant cause of invasive pneumococcal disease in sub-Saharan Africa, but the mechanism behind its increased invasiveness is not well understood. Here, we use mouse models of lung infection to identify virulence factors associated with severe bacteraemi...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7170840/ https://ncbi.nlm.nih.gov/pubmed/32312961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15751-6 |
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