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Bayesian Design of Biosimilars Clinical Programs Involving Multiple Therapeutic Indications
In this paper, we propose a Bayesian design framework for a biosimilars clinical program that entails conducting concurrent trials in multiple therapeutic indications to establish equivalent efficacy for a proposed biologic compared to a reference biologic in each indication to support approval of t...
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| Publicado no: | Biometrics |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7170751/ https://ncbi.nlm.nih.gov/pubmed/31631321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/biom.13163 |
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