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Bayesian clinical trial design using historical data that inform the treatment effect
We consider the problem of Bayesian sample size determination for a clinical trial in the presence of historical data that inform the treatment effect. Our broadly applicable, simulation-based methodology provides a framework for calibrating the informativeness of a prior while simultaneously identi...
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| 出版年: | Biostatistics |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6587921/ https://ncbi.nlm.nih.gov/pubmed/29547966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxy009 |
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