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Bayesian adaptive basket trial design using model averaging
In this article, we develop a Bayesian adaptive design methodology for oncology basket trials with binary endpoints using a Bayesian model averaging framework. Most existing methods seek to borrow information based on the degree of homogeneity of estimated response rates across all baskets. In reali...
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| Veröffentlicht in: | Biostatistics |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7846150/ https://ncbi.nlm.nih.gov/pubmed/31107534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxz014 |
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