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Bayesian clinical trial design using historical data that inform the treatment effect
We consider the problem of Bayesian sample size determination for a clinical trial in the presence of historical data that inform the treatment effect. Our broadly applicable, simulation-based methodology provides a framework for calibrating the informativeness of a prior while simultaneously identi...
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| Publicado no: | Biostatistics |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6587921/ https://ncbi.nlm.nih.gov/pubmed/29547966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxy009 |
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