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Crystal Structure of the 2′‐Specific and Double‐Stranded RNA‐Activated Interferon‐Induced Antiviral Protein 2′‐5′‐Oligoadenylate Synthetase

2′‐5′‐oligoadenylate synthetases are interferon‐induced, double‐stranded RNA‐activated antiviral enzymes which are the only proteins known to catalyse 2′‐specific nucleotidyl transfer. This first crystal structure of a 2′‐5′‐oligoadenylate synthetase reveals a structural conservation with the 3′‐spe...

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Publicat a:Scand J Immunol
Autors principals: Hartmann, R., Justesen, J., Sarkar, S., Sen, G., Yee, V.
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Ltd/Inc. 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7169539/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.0300-9475.2004.01423s.x
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