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Crystal Structure of the 2′‐Specific and Double‐Stranded RNA‐Activated Interferon‐Induced Antiviral Protein 2′‐5′‐Oligoadenylate Synthetase

2′‐5′‐oligoadenylate synthetases are interferon‐induced, double‐stranded RNA‐activated antiviral enzymes which are the only proteins known to catalyse 2′‐specific nucleotidyl transfer. This first crystal structure of a 2′‐5′‐oligoadenylate synthetase reveals a structural conservation with the 3′‐spe...

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Detalhes bibliográficos
Publicado no:Scand J Immunol
Main Authors: Hartmann, R., Justesen, J., Sarkar, S., Sen, G., Yee, V.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Ltd/Inc. 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7169539/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.0300-9475.2004.01423s.x
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