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HSD11B1 is upregulated synergistically by IFNγ and TNFα and mediates TSG-6 expression in human UC-MSCs

Inflammatory factors such as IFNγ and TNFα could endow mesenchymal stem cells (MSCs) a potent immunomodulatory property, a process called licensing, but the mechanisms are not fully understood. We here found that glucocorticoid-activating enzyme 11β-hydroxysteroid dehydrogenase type 1 (HSD11B1), whi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Death Discov
Egile Nagusiak: Huang, Peiqing, Li, Yinghong, Xu, Chenchang, Melino, Gerry, Shao, Changshun, Shi, Yufang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7168568/
https://ncbi.nlm.nih.gov/pubmed/32328292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-020-0262-7
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