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IFNγ and TNFα synergistically induce apoptosis of mesenchymal stem/stromal cells via the induction of nitric oxide

BACKGROUND: Mesenchymal stem/stromal cells (MSCs) have been widely used to treat various inflammatory diseases. The immunomodulatory capabilities of MSCs are usually licensed by inflammatory cytokines and may vary depending on the levels and the types of inflammatory cytokines. However, how the infl...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Li, Xiaolei, Shang, Bingxue, Li, Ya-nan, Shi, Yufang, Shao, Changshun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330503/
https://ncbi.nlm.nih.gov/pubmed/30635041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-1102-z
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