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IFNγ and TNFα synergistically induce apoptosis of mesenchymal stem/stromal cells via the induction of nitric oxide

BACKGROUND: Mesenchymal stem/stromal cells (MSCs) have been widely used to treat various inflammatory diseases. The immunomodulatory capabilities of MSCs are usually licensed by inflammatory cytokines and may vary depending on the levels and the types of inflammatory cytokines. However, how the infl...

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Библиографические подробности
Опубликовано в: :Stem Cell Res Ther
Главные авторы: Li, Xiaolei, Shang, Bingxue, Li, Ya-nan, Shi, Yufang, Shao, Changshun
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330503/
https://ncbi.nlm.nih.gov/pubmed/30635041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-1102-z
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