IFNγ and TNFα synergistically induce apoptosis of mesenchymal stem/stromal cells via the induction of nitric oxide

BACKGROUND: Mesenchymal stem/stromal cells (MSCs) have been widely used to treat various inflammatory diseases. The immunomodulatory capabilities of MSCs are usually licensed by inflammatory cytokines and may vary depending on the levels and the types of inflammatory cytokines. However, how the infl...

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Bibliografische gegevens
Gepubliceerd in:Stem Cell Res Ther
Hoofdauteurs: Li, Xiaolei, Shang, Bingxue, Li, Ya-nan, Shi, Yufang, Shao, Changshun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2019
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330503/
https://ncbi.nlm.nih.gov/pubmed/30635041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-1102-z
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