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Aminopeptidase‐N/CD13 (EC 3.4.11.2) inhibitors: Chemistry, biological evaluations, and therapeutic prospects

Aminopeptidase N (APN)/CD13 (EC 3.4.11.2) is a transmembrane protease present in a wide variety of human tissues and cell types (endothelial, epithelial, fibroblast, leukocyte). APN/CD13 expression is dysregulated in inflammatory diseases and in cancers (solid and hematologic tumors). APN/CD13 serve...

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Detalles Bibliográficos
Publicado en:Med Res Rev
Autores principales: Bauvois, Brigitte, Dauzonne, Daniel
Formato: Artigo
Lenguaje:Inglês
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2005
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7168514/
https://ncbi.nlm.nih.gov/pubmed/16216010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/med.20044
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