Neutralizing antibody against severe acute respiratory syndrome (SARS)‐coronavirus spike is highly effective for the protection of mice in the murine SARS model

We evaluated the efficacy of three SARS vaccine candidates in a murine SARS model utilizing low‐virulence Pp and SARS‐CoV coinfection. Vaccinated mice were protected from severe respiratory disease in parallel with a low virus titer in the lungs and a high neutralizing antibody titer in the plasma....

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Publicado en:Microbiol Immunol
Main Authors: Ishii, Koji, Hasegawa, Hideki, Nagata, Noriyo, Ami, Yasushi, Fukushi, Shuetsu, Taguchi, Fumihiro, Tsunetsugu‐Yokota, Yasuko
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Asia 2008
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7168451/
https://ncbi.nlm.nih.gov/pubmed/19291090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1348-0421.2008.00097.x
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