Neutralizing antibody against severe acute respiratory syndrome (SARS)‐coronavirus spike is highly effective for the protection of mice in the murine SARS model

We evaluated the efficacy of three SARS vaccine candidates in a murine SARS model utilizing low‐virulence Pp and SARS‐CoV coinfection. Vaccinated mice were protected from severe respiratory disease in parallel with a low virus titer in the lungs and a high neutralizing antibody titer in the plasma....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Microbiol Immunol
Egile Nagusiak: Ishii, Koji, Hasegawa, Hideki, Nagata, Noriyo, Ami, Yasushi, Fukushi, Shuetsu, Taguchi, Fumihiro, Tsunetsugu‐Yokota, Yasuko
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Blackwell Publishing Asia 2008
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7168451/
https://ncbi.nlm.nih.gov/pubmed/19291090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1348-0421.2008.00097.x
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