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Neutralizing antibody against severe acute respiratory syndrome (SARS)‐coronavirus spike is highly effective for the protection of mice in the murine SARS model

We evaluated the efficacy of three SARS vaccine candidates in a murine SARS model utilizing low‐virulence Pp and SARS‐CoV coinfection. Vaccinated mice were protected from severe respiratory disease in parallel with a low virus titer in the lungs and a high neutralizing antibody titer in the plasma....

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Detalhes bibliográficos
Publicado no:Microbiol Immunol
Main Authors: Ishii, Koji, Hasegawa, Hideki, Nagata, Noriyo, Ami, Yasushi, Fukushi, Shuetsu, Taguchi, Fumihiro, Tsunetsugu‐Yokota, Yasuko
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Asia 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7168451/
https://ncbi.nlm.nih.gov/pubmed/19291090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1348-0421.2008.00097.x
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