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Nickel-Catalyzed Three-Component Cycloadditions of Enoates, Alkynes, and Aldehydes

A method for the three-component cycloaddition of enoates, alkynes, and aldehydes has been developed. Building upon previous work by this group in which stoichiometrically generated metallacycles undergo alkylation, we report a catalytic, alkylative [3 + 2] cycloaddition. From simple starting materi...

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Vydáno v:J Org Chem
Hlavní autoři: Jenkins, Aireal D., Robo, Michael T., Zimmerman, Paul M., Montgomery, John
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7167596/
https://ncbi.nlm.nih.gov/pubmed/32004432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.9b02446
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