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Nickel-Catalyzed Reductive [2+2] Cycloaddition of Alkynes

The nickel-catalyzed synthesis of tetrasubstituted cyclobutenes from alkynes is reported. This transformation is uniquely promoted by the use of a primary aminophosphine, an unusual ligand in nickel catalysis. Mechanistic insights for this new transformation are provided, and post-reaction modificat...

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Bibliographic Details
Published in:J Am Chem Soc
Main Authors: Cañellas, Santiago, Montgomery, John, Pericàs, Miquel À.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470007/
https://ncbi.nlm.nih.gov/pubmed/30517785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b09677
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