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Transcription factor-mediated regulation of the BCRP/ABCG2 efflux transporter: a review across tissues and species

INTRODUCTION: The breast cancer resistance protein (BCRP/ABCG2) is a member of the ATP-binding cassette superfamily of transporters. Using the energy garnered from the hydrolysis of ATP, BCRP actively removes drugs and endogenous molecules from the cell. With broad expression across the liver, kidne...

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Detalhes bibliográficos
Publicado no:Expert Opin Drug Metab Toxicol
Main Authors: Gorczyca, Ludwik, Aleksunes, Lauren M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7167287/
https://ncbi.nlm.nih.gov/pubmed/32077332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17425255.2020.1732348
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