Down-Regulation of the Placental BCRP/ABCG2 Transporter in Response to Hypoxia Signaling

INTRODUCTION: The BCRP/ABCG2 efflux transporter protects the developing fetus by limiting the transplacental transfer of drugs and chemicals and prevents the apoptosis of trophoblasts. The purpose of this study was to determine whether hypoxia-related signaling alters placental BCRP expression and f...

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Detalhes bibliográficos
Publicado no:Placenta
Main Authors: Francois, Lissa N., Gorczyca, Ludwik, Du, Jianyao, Bircsak, Kristin M., Yen, Elizabeth, Wen, Xia, Tu, Mei-Juan, Yu, Ai-Ming, Illsley, Nicholas P., Zamudio, Stacy, Aleksunes, Lauren M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354084/
https://ncbi.nlm.nih.gov/pubmed/28292469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.placenta.2017.01.125
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