Placental BCRP/ABCG2 Transporter Prevents Fetal Exposure to the Estrogenic Mycotoxin Zearalenone

In the placenta, the breast cancer resistance protein (BCRP)/ABCG2 efflux transporter limits the maternal-to-fetal transfer of drugs and chemicals. Previous research has pointed to the estrogenic mycotoxin zearalenone as a potential substrate for BCRP. Here, we sought to assess the role of the BCRP...

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Bibliografiske detaljer
Udgivet i:Toxicol Sci
Main Authors: Szilagyi, John T, Gorczyca, Ludwik, Brinker, Anita, Buckley, Brian, Laskin, Jeffrey D, Aleksunes, Lauren M
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Placental Transporters and Zearalenone Toxicity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6432861/
https://ncbi.nlm.nih.gov/pubmed/30576553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfy303
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