Ivacaftor decreases monocyte sensitivity to interferon-γ in people with cystic fibrosis

This study demonstrates that initiation of the CFTR modulator ivacaftor in people with cystic fibrosis and susceptible CFTR mutations causes an acute reduction in blood monocyte sensitivity to the key proinflammatory cytokine IFN-γ http://bit.ly/2TeI6LG

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Detalhes bibliográficos
Publicado no:ERJ Open Res
Main Authors: Hisert, Katherine B., Birkland, Timothy P., Schoenfelt, Kelly Q., Long, Matthew E., Grogan, Brenda, Carter, Suzanne, Liles, W. Conrad, McKone, Edward F., Becker, Lev, Manicone, Anne M.
Formato: Artigo
Idioma:Inglês
Publicado em: European Respiratory Society 2020
Assuntos:
Original Research Letters
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7167213/
https://ncbi.nlm.nih.gov/pubmed/32337217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/23120541.00318-2019
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