Ivacaftor decreases monocyte sensitivity to interferon-γ in people with cystic fibrosis

This study demonstrates that initiation of the CFTR modulator ivacaftor in people with cystic fibrosis and susceptible CFTR mutations causes an acute reduction in blood monocyte sensitivity to the key proinflammatory cytokine IFN-γ http://bit.ly/2TeI6LG

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Dades bibliogràfiques
Publicat a:ERJ Open Res
Autors principals: Hisert, Katherine B., Birkland, Timothy P., Schoenfelt, Kelly Q., Long, Matthew E., Grogan, Brenda, Carter, Suzanne, Liles, W. Conrad, McKone, Edward F., Becker, Lev, Manicone, Anne M.
Format: Artigo
Idioma:Inglês
Publicat: European Respiratory Society 2020
Matèries:
Original Research Letters
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7167213/
https://ncbi.nlm.nih.gov/pubmed/32337217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/23120541.00318-2019
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